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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd7f1e952a8d6ef992b8e66387b9625b6fc53fac72b7759bdec035c17265a9c5' 
  AND token = '2r66FNPEX2bYDdvXY/PYOxH2MdPL+Z7MHxAIWgoxJ6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}