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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78d1c20c125ec5b27de23c3f5ca9cf378a8a985d7a19e6d2858d0e9f0056c2a' 
  AND token = 'HUtgn3TQHlAXSIBw9+5E6ZGRiP7NptI3tYyyDFlUnbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}