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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0df0c084e185dab295f853f046de8bdacac6c6f8f02a508b3c567a3f75f52b5' 
  AND token = 'O7jbdPpVfyfwvl5ue/G/Z/Xj1b/DsuMtiICneCmXCpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}