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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777268a92dbde049f2aca0c3e8d4f11150a8c88f5c5487692b81badf2f6a9c3d' 
  AND token = 'ecBh2u5JAAXiJ223hry60yuXMQGXTYdb94viXSvD5G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}