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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6319e68c7e6131dd1545f500b36618b16aaec088e65ee8b592e90a9565ad74b' 
  AND token = 'TSUW56/OsyVwTmQoxqU6rkuLPNK5XViGxtUAENoM13k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}