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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd722b72eccce100b94f17abba64eb01b78b36128cc5730152d5b4ea70d7cc22' 
  AND token = 'GMRUH3y47KnsQxu80lzjyL+7QvvLy437P+X7aJzVoL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}