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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c9524610fbdc5ab529d406d96a2e427f16225f6a6381785cfab7a5e25011340' 
  AND token = 'IhzNDuhUAXAN1LIsrcnF51wPbWJ6X9b9MAqGMkkr1jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}