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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a70d617738de7502ec1995bc131809b6ed0ab0e3e7beb30c39ed3025c48c2d' 
  AND token = 'GMyN5VtaDSBpJwTkeE1CVQNc1qJ3UB38XT1EH1h066g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}