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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '115c43233f61fb21d8832cbb83141576450dc74f57b0542cd031d2d0bc6085f9' 
  AND token = 'EfVZ4JJeIBRkQX6f7PizXLzrWyVdAsJOEnYN1OBNKyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}