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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c1821d67ba00c2e16ed6ccf10c3a17c027e6de99d3dcf80d24c178ed9269cb5' 
  AND token = 'G3wE8OvKb9k+17juai/B9KDq1SPFjy2RiAISwkFBks8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}