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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b22370a534492fd8249e03547a1cac4f2576f02c73cfa0cae7e85190f6517f0' 
  AND token = 'oKo5Mlelo/rB/8HDl5LhHB7u4fTO7f0fbyRmdOBmdJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}