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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6359a1aead47af5fb2018a01bbcc013f61d2214437112f719500db8adfa243d1' 
  AND token = 'J0Iusu7ck9qF97Is0bR/dvbMIa4ry7XI8iAxU25mBu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}