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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2e67a49ed5cd87085ead0c21f9a8aaeb5f492242d1f57b2e93475d7eebdcb7' 
  AND token = 'i8DmN+CtOejTLVWMeqm+cNWjAmtUTyQKWPhlNU3gwmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}