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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5119b594da1f73b0e226f09ef3c1e47062b81074267c278b22ed5827a0141a64' 
  AND token = 'gNg/0IiuKrV605zxRC+M5nRAx1mG9vJVD18eXtOM/x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}