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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '576ddc253b330129fb50ed5d9201b6545ea45b49aa4bb3540693a898015355e8' 
  AND token = '+F7eJIMBHVswa93f2dQf6YxHuRbgLlUJEtzy2UhCdj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}