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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078162445da70b458e18a3fcd5ed1bcf3afe9ac98c5c34bacf71fa94eb67d174' 
  AND token = 'UlueborFyH3me8FtPMuvPyNVlqqFyH3ona5mAzU/xoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}