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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b17023b83127160fdba1121d473bd65ddaf415fb017cc67ca66ecaa6f1449ede' 
  AND token = 'mIbG4l/EOmRAyuLYOIQL13qe/++6mu1Ie1Vp55WgQeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}