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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c499a4e9f54d1f20a906f5af712fd36db825fc62865a19e5afe41eaca7881fd' 
  AND token = 'XqMdiBqePT4y7x74YmjkQI5zU/S8/nQwoGF2D9lKHAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}