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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfef507254b7c5447b47f51ad82ce1e79cfd13b1e261a5520af5304701674302' 
  AND token = 'fRkd7RNiu4c2FVZ0vXtDQg+I7gH29dKUhV+5UAU42FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}