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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ada36a182b31d08d68f3d9b0985f4cabc012b1fe45799dfdb2cfe7f227ca5c26' 
  AND token = '6NNe+I70jp76U42n0B0Aq4gfOnUjiut3mVnCiW/AXYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}