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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce7a350d81329b66a3e757ba84fff5baafc9eb28825f05c6a71dd4de2cfbac6' 
  AND token = 'a7bvINN7z6Vv8eB+xQqoshbt9aAAH6KRQoZF+ArH2KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}