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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd111c4a02f98b90035bfab71edff3c6f31c375bb775f1df34a58d75a73cf3a58' 
  AND token = 'sv1SWyfLva/PPiUdT4o+GY5DZKprGfQPRzsCAxOiuzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}