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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9116c0f86a1d5729f2396691c63bd842e3ced51404bee66f42a0f61138037d78' 
  AND token = 'tYUuSWp0QmxI1hF36Zt2XIcPf+JtChJjN1wdFX2z4xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}