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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e667a80c5686bdce33b4c18cf4c76ae89e40254ca62489e04f18c0810baddc' 
  AND token = 'PB3NIPPCYt4+yvbznUxlebVPCDH1JwANK5TJcU49IAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}