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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653ca6ff4a5bc4989a3bd2f30ad4d6f3629065d4c157228226eb6c6da24d8bdf' 
  AND token = 'xQ0XjdYGdeqM3HMsoc/TekDglx/nsCBa7/zbTvlKV9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}