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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd254bc921530427ae66e603bcfec05f6383f1a05bb4d62a59e1d9ffb89768500' 
  AND token = 'ehOS/0hPbrBNPkHSyGSz+zMT/XZj2TFE1SSCKGiqHb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}