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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5970cda4ec39f73547d080a3572867e8d5920610314f11b9f4d2fe315ade3f0d' 
  AND token = 'nsAnQvoSVv9s7KGQr5WxWes7yoSJRzSTaU2hqBXglQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}