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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11069909240ce49d69a9b6ac9ca3c5eb900d2d46546a3d1c042d61278e0bdc72' 
  AND token = 'wRQbfEtk0BUdMwxvcYR0narqFgix4ahB6rmvy+gjV7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}