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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d19f1be25d3b680d35dca39ada7d4befa6f0d12f36ff29fb960984e0db9959b' 
  AND token = 'y9uLliuLf1Qs923kdmR1+6c4xeNuHYTh7INysma3Vjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}