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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca86550e09d9dfde83d6b2489fcaff74510ef3174e005efd52f42d0fe748bc6' 
  AND token = 'HOz06n8NdlE1QOPyFRefc0LxepcXGOWyykypSFX9yB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}