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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0724e1d771c9c6f755788dda2c8c783e8c8f3eec7652325d68440840af1c2892' 
  AND token = 'rPnwjlwZReVM5kv6dlc/ixvyUtBF0tIEJlKWUh1O7V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}