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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c75d00957a1419e761b697524c7b94273e2167b55c2e35b4f21e016612e8cb' 
  AND token = 'vYI2wW3CcxmAMbLV1G4rjEKF2We3+sR1kDHVbf2VZVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}