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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4c977995ccf94e62eaae4e098db69ede99151961b602d72c1b2a7378a7b6ae' 
  AND token = 'VtyTbtllv9T7Fx6g0nxfQ511DP1slXVYT3PGb0cKM4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}