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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfdb6de76e017df168c6af17ab51f056ac5fdad89a332bd030d9a4525af1401f' 
  AND token = 'Al/odFNC7Tr61e8LYLCGmATsmcpBOgrBzQXAnjSoCkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}