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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c9e0d17467e00c206cd3039a703a52be3cace248696b0a20e768ae6466b991' 
  AND token = '9FYC7IRA5xMc8aBsAF8gEgQjfFv0/SZ6fqM6eKrRij4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}