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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed55fe129869fd455b2a3772ed314230445a9ffde6838294bfc0fb076fea4695' 
  AND token = '5y9o7OfjTqp2JbdC0/Zh7dbw/H62hW+MmeqmhHXFDrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}