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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8bd05b4620080a24dedccd25c2436975782c44a07dcea1a2ac83f122c95eb42' 
  AND token = '+IeaYhdtLT9pNiu54Vpli7uAJ1yL4+zpqA/wRHHygko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}