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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e071c7b6510ce160a5b6804fed14054aefe1d68d72dfd8ef63366959973ea28' 
  AND token = 'VcKRHdaQ/D30e+9v4R1RQA4yAzSv0ldqkqbfXUBAThs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}