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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e3235d169569db92eacf3897188f766c7e1045af8f61e190acf956f7b3618a' 
  AND token = '3hronlgDBNDptMOTXxoOInomDLTzz+zagvZps0HjHtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}