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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1664c3fce5ae772304e517c1ed2024655937fb3775b9476ba3412254f4d60b67' 
  AND token = 'MRrgEK5yHpb8r9TNuhflb00dS0iW1iE/4Qso3yrHeac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}