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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001c0c700a37d02cdec66e3ede1e63a4e2e44014f5f83f06106a14eb7316130f' 
  AND token = '7KkiLmxR2NMUP9aiIx17HXfYFg/3iFCm6i/8ZME9568=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}