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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd9a495c9c3533374e9daf9d993b5d2c6fb794e9c54a352529579a5788f0011' 
  AND token = '+snliLM1PrY3aVZP26ezemPGoF1GnBkaeOpCDLYImAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}