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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250e364c34269afa4995d8d3228440612a21af3b2258d8c38e269883d05d157b' 
  AND token = 'aNZbWZ1ltY6QGe7DWgB7Rxe51fgNpkbI6W6/xjk2wx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}