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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40c0908dc9e3460bc2deacb983d4483dff6abd7e5290c09a39542551e026dccd' 
  AND token = 'HRjN/JKOPgarGRk+215Y9DOprIdrxtDXFjagGE6Hmxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}