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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd15f50b7f2227b2836d2780424994be9bade6e81d436a2515234bf058b16fe9f' 
  AND token = 'bZJMwi9DTO0L7DkLulwMHCrvM0/eDr0eWTPoo7gd7Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}