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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a65c74f53dcf5bd76b77bdee679d58b6545c773c17ffbf8b6428b5115a293e8c' 
  AND token = 'vtPeujb57RU3QM2vJSFSxIZ1fwB8sf0aVhSCyP7Ym1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}