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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16668fb94c47bec1d108599aea31ac0b1c23f19367912932fe1a0defd6897ad6' 
  AND token = 'QUUPGlOnEU+waAwu6NUkl3W9xft0NaN/QqqSa46BQpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}