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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726b7558237df5b60befb10edd44834775788a2baa880f9b7d2373e6fbcf2760' 
  AND token = 'RWKXVzD4OBJhhnrBFyyy8b86gNw4S2bwt+euxWr3z5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}