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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721d35e87912483537607a59ed86b8be34bc6b65943cb468fcdf8760f0076d72' 
  AND token = '8VrEWd8f/a87LUoEvc9h8OeVuKFf2cHGwqaz6ekOzGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}