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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46fa42987db9a1c88ddbb192def244447eec7eaaba28e6f1e0522eb7aa0bff6b' 
  AND token = 'xtx8205Dx/nQg5vhOvlbg2A6LnUA3KUxo2W3ML9/Tsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}